More evidence against BT

Posted on October 21st, 2007 in news, pesticide by Anastasia

Genetically engineered corn could harm aquatic ecosystems.” Catchy title, right? In summary, the scientists found that caddisflies, a common prey of freshwater fish, can be killed when they eat parts of transgenic corn plants that are expressing the BT toxin. This is certainly a problem, but one that has solutions.

First of all, the actual BT protein comes in many varieties, as described in this article by Virginia Cooperative Extension. Changes in the protein can change the target organism. Some can kill all caterpillars, some kill only one species. So, the most simple solution is to use a version of BT that specifically targets corn pests and not non-target organisms like caddisflies.

The article didn’t mention which types of BT were tested on caddisflies, or which types of BT are most commonly used in the fields. It doesn’t matter as much as they imply in the article anyway, as there are lots of different types of caddisflies. They eat all different things from algae to plant matter to other insects. So it is highly unlikely that all caddisfly species will suddenly decide to start eating corn leaves, especially ones that kill them. Even if they did all decide to start eating corn leaves that floated down the river, farmers could be more careful about loose leaves blowing off their land during harvest.

The problem could also be alleviated by using tissue and time specific promoters. For example, if the larvae damage corn at a specific life stage of the corn, then use a promoter that is only on during that life stage. If the pests only eat the roots, then use a promoter that only produces the protein in the roots. Or, try less strong promoters that produce the lowest level of BT possible that will still be effective against the target pest.

Finally, the research didn’t consider that overall insecticide use is decreased when BT crops are used. What is the caddisfly death rate from insecticides running off of fields compared to the number of caddisflies that are killed by eating leaves from BT corn? How many other non-target insects are killed by that run off, how many other food webs are affected? How much ground and surface water is contaminated by insecticides, how many human children are affected by the pesticides? BT has no effect on mammals, but organophosphates and other insecticides do. Not to mention the fact that BT corn sustains less fungal damage than conventional corn, leading to fewer poisonings by mycotoxins and better yields.

I don’t deny that the system needs to be perfected, but to throw BT aside based on studies such as this would be folly.

Mini-chromosomes

Posted on October 21st, 2007 in technology by Anastasia

Where a transgene incorporates into a plant’s chromosomes can not be controlled. So, scientists have to transform many plants, and hope that at least one individual didn’t have the transgene interrupt a native gene. One solution to this problem is called a mini-chromosome. This technique uses the natural centromere sequence of an organism to build an entirely new chromosome that would be passed on to successive generations. The mini-chromosome can then be filled with a combination of genes, knowing that no native genes will be interrupted. Plants could be transformed with entire pathways, using this technology. The applications include improving field traits and nutrition, as well as things like making biofuels and bioplastics.

This research has been going on for a while, but the newest publishing shows that the mini-chromosome can be passed on to the next generation as a normal chromosome. From SD, Transgenics Transformed:

The maize mini-chromosome, once introduced, behaves much like an ordinary chromosome. It remains distinct from the other chromosomes. Its gene cassette is structurally stable from generation to generation. The genes it carries are expressed and it is transmitted through mitosis and meiosis.

The scientists started a company called Chromatin, which sold non-exclusive rights to Monsanto in May. Other companies are looking to get involved.

I’m really excited about this idea. One of the problems with genetic engineering is our inability to control where a gene inserts into the genome. Mini-chromosomes eliminate that problem and allow the scientist to add many genes instead of just one. It would be nice if they were still hiring when I am ready to graduate!

News: GMO poplar trees, recycling, stress reduction

Posted on October 16th, 2007 in Environment, news by Anastasia

Poplar trees genetically engineered to remove carcinogens from groundwater. The trees have been genetically engineered with a gene for an enzyme that breaks down contaminants in groundwater. The gene is actually from rabbits, where the enzyme breaks down toxins in the rabbit’s liver. The next step of the project is to find an applicable gene in the poplar genome so they can make plants that are cisgenic instead of transgenic.

Plastics recycling industry starving for materials. Even though plastics can be recycled into new containers, only 25% of plastic waste makes it to recycling centers. I think people forget that plastic is made from petroleum. When we run out of oil, we also run out of plastic. Corn plastics are still a way off, so we should conserve what we have!

Expecting an afternoon nap can reduce blood pressure. People who regularly take afternoon naps have decreased mortality due to heart attacks. This study shows that the decrease in blood pressure actually happens right before a person goes to sleep, simply because they are expecting the sleep.